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Advances in functional genetic screening with transposons and CRISPR/Cas9 to illuminate cancer biology

Large-scale genome sequencing studies have identified a wealth of mutations in human tumors and have dramatically advanced the field of cancer genetics. However, the functional consequences of an altered gene in tumor progression cannot always be inferred from mutation status alone. This underscores...

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Dades bibliogràfiques
Publicat a:Curr Opin Genet Dev
Autor principal: O’Donnell, Kathryn A
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312197/
https://ncbi.nlm.nih.gov/pubmed/29587177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2018.03.006
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