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Chromosome engineering in zygotes with CRISPR/Cas9
Deletions, duplications, and inversions of large genomic regions covering several genes are an important class of disease causing variants in humans. Modeling these structural variants in mice requires multistep processes in ES cells, which has limited their availability. Mutant mice containing smal...
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| 出版年: | Genesis |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4819711/ https://ncbi.nlm.nih.gov/pubmed/26742453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22915 |
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