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Chromosome engineering in zygotes with CRISPR/Cas9

Deletions, duplications, and inversions of large genomic regions covering several genes are an important class of disease causing variants in humans. Modeling these structural variants in mice requires multistep processes in ES cells, which has limited their availability. Mutant mice containing smal...

詳細記述

保存先:
書誌詳細
出版年:Genesis
主要な著者: Boroviak, Katharina, Doe, Brendan, Banerjee, Ruby, Yang, Fengtang, Bradley, Allan
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819711/
https://ncbi.nlm.nih.gov/pubmed/26742453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22915
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