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Engineering new balancer chromosomes in C. elegans via CRISPR/Cas9

Balancer chromosomes are convenient tools used to maintain lethal mutations in heterozygotes. We established a method for engineering new balancers in C. elegans by using the CRISPR/Cas9 system in a non-homologous end-joining mutant. Our studies will make it easier for researchers to maintain lethal...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Iwata, Satoru, Yoshina, Sawako, Suehiro, Yuji, Hori, Sayaka, Mitani, Shohei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030659/
https://ncbi.nlm.nih.gov/pubmed/27650892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33840
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