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Engineering new balancer chromosomes in C. elegans via CRISPR/Cas9
Balancer chromosomes are convenient tools used to maintain lethal mutations in heterozygotes. We established a method for engineering new balancers in C. elegans by using the CRISPR/Cas9 system in a non-homologous end-joining mutant. Our studies will make it easier for researchers to maintain lethal...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5030659/ https://ncbi.nlm.nih.gov/pubmed/27650892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33840 |
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