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Engineering new balancer chromosomes in C. elegans via CRISPR/Cas9

Balancer chromosomes are convenient tools used to maintain lethal mutations in heterozygotes. We established a method for engineering new balancers in C. elegans by using the CRISPR/Cas9 system in a non-homologous end-joining mutant. Our studies will make it easier for researchers to maintain lethal...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Iwata, Satoru, Yoshina, Sawako, Suehiro, Yuji, Hori, Sayaka, Mitani, Shohei
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030659/
https://ncbi.nlm.nih.gov/pubmed/27650892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33840
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