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Chromosome engineering in zygotes with CRISPR/Cas9
Deletions, duplications, and inversions of large genomic regions covering several genes are an important class of disease causing variants in humans. Modeling these structural variants in mice requires multistep processes in ES cells, which has limited their availability. Mutant mice containing smal...
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| Опубликовано в: : | Genesis |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4819711/ https://ncbi.nlm.nih.gov/pubmed/26742453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22915 |
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