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Chromosome drives via CRISPR-Cas9 in yeast

Self-propagating drive systems are capable of causing non-Mendelian inheritance. Here, we report a drive system in yeast referred to as a chromosome drive that eliminates the target chromosome via CRISPR-Cas9, enabling the transmission of the desired chromosome. Our results show that the entire Sacc...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Xu, Hui, Han, Mingzhe, Zhou, Shiyi, Li, Bing-Zhi, Wu, Yi, Yuan, Ying-Jin
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455567/
https://ncbi.nlm.nih.gov/pubmed/32859906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18222-0
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