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Safeguarding CRISPR-Cas9 gene drives in yeast

RNA-guided gene drives capable of spreading genomic alterations made in laboratory organisms through wild populations in an inheritable way could be used to control populations of organisms that cause environmental and public health problems. However, the possibility of unintended genome editing thr...

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Detalhes bibliográficos
Publicado no:Nat Biotechnol
Main Authors: DiCarlo, James E., Chavez, Alejandro, Dietz, Sven L., Esvelt, Kevin M., Church, George M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675690/
https://ncbi.nlm.nih.gov/pubmed/26571100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3412
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