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Safeguarding CRISPR-Cas9 gene drives in yeast

RNA-guided gene drives capable of spreading genomic alterations made in laboratory organisms through wild populations in an inheritable way could be used to control populations of organisms that cause environmental and public health problems. However, the possibility of unintended genome editing thr...

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Bibliografische gegevens
Gepubliceerd in:Nat Biotechnol
Hoofdauteurs: DiCarlo, James E., Chavez, Alejandro, Dietz, Sven L., Esvelt, Kevin M., Church, George M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675690/
https://ncbi.nlm.nih.gov/pubmed/26571100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3412
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