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CRISPR/Cas9-mediated targeted chromosome elimination
BACKGROUND: The CRISPR/Cas9 system has become an efficient gene editing method for generating cells carrying precise gene mutations, including the rearrangement and deletion of chromosomal segments. However, whether an entire chromosome could be eliminated by this technology is still unknown. RESULT...
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| Wydane w: | Genome Biol |
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| Główni autorzy: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BioMed Central
2017
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5701507/ https://ncbi.nlm.nih.gov/pubmed/29178945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1354-4 |
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