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CRISPR/Cas9-mediated targeted chromosome elimination
BACKGROUND: The CRISPR/Cas9 system has become an efficient gene editing method for generating cells carrying precise gene mutations, including the rearrangement and deletion of chromosomal segments. However, whether an entire chromosome could be eliminated by this technology is still unknown. RESULT...
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| 出版年: | Genome Biol |
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| 主要な著者: | , , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5701507/ https://ncbi.nlm.nih.gov/pubmed/29178945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1354-4 |
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