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Reduction of integrin alpha 4 activity through splice modulating antisense oligonucleotides

With recent approvals of antisense oligonucleotides as therapeutics, there is an increasing interest in expanding the application of these compounds to many other diseases. Our laboratory focuses on developing therapeutic splice modulating antisense oligonucleotides to treat diseases potentially ame...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Aung-Htut, May T., Comerford, Iain, Johnsen, Russell, Foyle, Kerrie, Fletcher, Sue, Wilton, Steve D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736852/
https://ncbi.nlm.nih.gov/pubmed/31506448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49385-6
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