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Reduction of integrin alpha 4 activity through splice modulating antisense oligonucleotides

With recent approvals of antisense oligonucleotides as therapeutics, there is an increasing interest in expanding the application of these compounds to many other diseases. Our laboratory focuses on developing therapeutic splice modulating antisense oligonucleotides to treat diseases potentially ame...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Aung-Htut, May T., Comerford, Iain, Johnsen, Russell, Foyle, Kerrie, Fletcher, Sue, Wilton, Steve D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736852/
https://ncbi.nlm.nih.gov/pubmed/31506448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49385-6
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