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Reduction of integrin alpha 4 activity through splice modulating antisense oligonucleotides

With recent approvals of antisense oligonucleotides as therapeutics, there is an increasing interest in expanding the application of these compounds to many other diseases. Our laboratory focuses on developing therapeutic splice modulating antisense oligonucleotides to treat diseases potentially ame...

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Detalles Bibliográficos
Publicado en:Sci Rep
Autores principales: Aung-Htut, May T., Comerford, Iain, Johnsen, Russell, Foyle, Kerrie, Fletcher, Sue, Wilton, Steve D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736852/
https://ncbi.nlm.nih.gov/pubmed/31506448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49385-6
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