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Induction of cryptic pre-mRNA splice-switching by antisense oligonucleotides
Antisense oligomers (AOs) are increasingly being used to modulate RNA splicing in live cells, both for research and for the development of therapeutics. While the most common intended effect of these AOs is to induce skipping of whole exons, rare examples are emerging of AOs that induce skipping of...
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| Опубликовано в: : | Sci Rep |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8302632/ https://ncbi.nlm.nih.gov/pubmed/34302060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94639-x |
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