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Induction of cryptic pre-mRNA splice-switching by antisense oligonucleotides

Antisense oligomers (AOs) are increasingly being used to modulate RNA splicing in live cells, both for research and for the development of therapeutics. While the most common intended effect of these AOs is to induce skipping of whole exons, rare examples are emerging of AOs that induce skipping of...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Ham, Kristin A., Keegan, Niall P., McIntosh, Craig S., Aung-Htut, May T., Zaw, Khine, Greer, Kane, Fletcher, Sue, Wilton, Steve D.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302632/
https://ncbi.nlm.nih.gov/pubmed/34302060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94639-x
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