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Induction of cryptic pre-mRNA splice-switching by antisense oligonucleotides

Antisense oligomers (AOs) are increasingly being used to modulate RNA splicing in live cells, both for research and for the development of therapeutics. While the most common intended effect of these AOs is to induce skipping of whole exons, rare examples are emerging of AOs that induce skipping of...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Ham, Kristin A., Keegan, Niall P., McIntosh, Craig S., Aung-Htut, May T., Zaw, Khine, Greer, Kane, Fletcher, Sue, Wilton, Steve D.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302632/
https://ncbi.nlm.nih.gov/pubmed/34302060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94639-x
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