SIRT7 mediates L1 elements transcriptional repression and their association with the nuclear lamina

Long interspersed elements-1 (LINE-1, L1) are retrotransposons that hold the capacity of self-propagation in the genome with potential mutagenic outcomes. How somatic cells restrict L1 activity and how this process becomes dysfunctional during aging and in cancer cells is poorly understood. L1s are...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Vazquez, Berta N, Thackray, Joshua K, Simonet, Nicolas G, Chahar, Sanjay, Kane-Goldsmith, Noriko, Newkirk, Simon J, Lee, Suman, Xing, Jinchuan, Verzi, Michael P, An, Wenfeng, Vaquero, Alejandro, Tischfield, Jay A, Serrano, Lourdes
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735864/
https://ncbi.nlm.nih.gov/pubmed/31226208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz519
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados