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Sirtuins and DNA damage repair: SIRT7 comes to play

Aging is characterized by a cumulative loss of genome integrity, which involves chromatin reorganization, transcriptional dysregulation and the accumulation of DNA damage. Sirtuins participate in the protection against these aging processes by promoting genome homeostasis in response to cellular str...

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Bibliografiske detaljer
Udgivet i:Nucleus
Main Authors: Vazquez, Berta N., Thackray, Joshua K., Serrano, Lourdes
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403131/
https://ncbi.nlm.nih.gov/pubmed/28406750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2016.1264552
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