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Sirtuins and DNA damage repair: SIRT7 comes to play
Aging is characterized by a cumulative loss of genome integrity, which involves chromatin reorganization, transcriptional dysregulation and the accumulation of DNA damage. Sirtuins participate in the protection against these aging processes by promoting genome homeostasis in response to cellular str...
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| Veröffentlicht in: | Nucleus |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5403131/ https://ncbi.nlm.nih.gov/pubmed/28406750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2016.1264552 |
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