Complement Component C5 and TLR Molecule CD14 Mediate Heme-Induced Thromboinflammation in Human Blood

Heme is a critical danger molecule liberated from hemeproteins in various conditions, including from hemoglobin in hemolytic diseases. Heme may cause thromboinflammatory damage by activating inflammatory and hemostatic pathways, such as complement, the TLRs, coagulation, and platelets. In this study...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Thomas, Anub M., Gerogianni, Alexandra, McAdam, Martin B., Fløisand, Yngvar, Lau, Corinna, Espevik, Terje, Nilsson, Per H., Mollnes, Tom Eirik, Barratt-Due, Andreas
Format: Artigo
Idioma:Inglês
Publicat: AAI 2019
Matèries:
Innate Immunity and Inflammation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731449/
https://ncbi.nlm.nih.gov/pubmed/31413105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900047
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