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Regulation of Eag1 gating by its intracellular domains

Voltage-gated potassium channels (K(v)s) are gated by transmembrane voltage sensors (VS) that move in response to changes in membrane voltage. K(v)10.1 or Eag1 also has three intracellular domains: PAS, C-linker, and CNBHD. We demonstrate that the Eag1 intracellular domains are not required for volt...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Whicher, Jonathan R, MacKinnon, Roderick
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731095/
https://ncbi.nlm.nih.gov/pubmed/31490124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49188
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