Subclinical Bovine Spongiform Encephalopathy Infection in Transgenic Mice Expressing Porcine Prion Protein

The bovine-porcine species barrier to bovine spongiform encephalopathy (BSE) infection was explored by generating transgenic mouse lines expressing the porcine prion protein (PrP) gene. All of the porcine transgenic (poTg) mice showed clinical signs of BSE after intracerebral inoculation with a high...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Castilla, Joaquín, Gutiérrez-Adán, Alfonso, Brun, Alejandro, Doyle, Deirdre, Pintado, Belén, Ramírez, Miguel A., Salguero, Francisco J., Parra, Beatriz, Segundo, Fayna Díaz San, Sánchez-Vizcaíno, José M., Rogers, Mark, Torres, Juan M.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2004
Fag:
Neurobiology of Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729370/
https://ncbi.nlm.nih.gov/pubmed/15163699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5400-03.2004
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