Subclinical Bovine Spongiform Encephalopathy Infection in Transgenic Mice Expressing Porcine Prion Protein

The bovine-porcine species barrier to bovine spongiform encephalopathy (BSE) infection was explored by generating transgenic mouse lines expressing the porcine prion protein (PrP) gene. All of the porcine transgenic (poTg) mice showed clinical signs of BSE after intracerebral inoculation with a high...

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Pubblicato in:J Neurosci
Autori principali: Castilla, Joaquín, Gutiérrez-Adán, Alfonso, Brun, Alejandro, Doyle, Deirdre, Pintado, Belén, Ramírez, Miguel A., Salguero, Francisco J., Parra, Beatriz, Segundo, Fayna Díaz San, Sánchez-Vizcaíno, José M., Rogers, Mark, Torres, Juan M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2004
Soggetti:
Neurobiology of Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729370/
https://ncbi.nlm.nih.gov/pubmed/15163699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5400-03.2004
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