Vertical Transmission of Bovine Spongiform Encephalopathy Prions Evaluated in a Transgenic Mouse Model

In this work we show evidence of mother-to-offspring transmission in a transgenic mouse line expressing bovine PrP (boTg) experimentally infected by intracerebral administration of bovine spongiform encephalopathy (BSE) prions. PrP(res) was detected in brains of newborns from infected mothers only w...

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Hlavní autoři: Castilla, J., Brun, A., Díaz-San Segundo, F., Salguero, F. J., Gutiérrez-Adán, A., Pintado, B., Ramírez, M. A., del Riego, L., Torres, J. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143732/
https://ncbi.nlm.nih.gov/pubmed/15956610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.13.8665-8668.2005
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