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Sheep-Passaged Bovine Spongiform Encephalopathy Agent Exhibits Altered Pathobiological Properties in Bovine-PrP Transgenic Mice

Sheep can be experimentally infected with bovine spongiform encephalopathy (BSE), and the ensuing disease is similar to scrapie in terms of pathogenesis and clinical signs. BSE infection in sheep is an animal and human health concern. In this study, the transmission in BoPrP-Tg110 mice of prions fro...

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Detalhes bibliográficos
Main Authors: Espinosa, Juan Carlos, Andréoletti, Olivier, Castilla, Joaquín, Herva, María Eugenia, Morales, Mónica, Alamillo, Elia, San-Segundo, Fayna Díaz, Lacroux, Caroline, Lugan, Séverine, Salguero, Francisco Javier, Langeveld, Jan, Torres, Juan María
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797487/
https://ncbi.nlm.nih.gov/pubmed/17079295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01356-06
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