Sheep-Passaged Bovine Spongiform Encephalopathy Agent Exhibits Altered Pathobiological Properties in Bovine-PrP Transgenic Mice

Sheep can be experimentally infected with bovine spongiform encephalopathy (BSE), and the ensuing disease is similar to scrapie in terms of pathogenesis and clinical signs. BSE infection in sheep is an animal and human health concern. In this study, the transmission in BoPrP-Tg110 mice of prions fro...

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Bibliographic Details
Main Authors: Espinosa, Juan Carlos, Andréoletti, Olivier, Castilla, Joaquín, Herva, María Eugenia, Morales, Mónica, Alamillo, Elia, San-Segundo, Fayna Díaz, Lacroux, Caroline, Lugan, Séverine, Salguero, Francisco Javier, Langeveld, Jan, Torres, Juan María
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797487/
https://ncbi.nlm.nih.gov/pubmed/17079295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01356-06
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