Protective Effect of Val(129)-PrP against Bovine Spongiform Encephalopathy but not Variant Creutzfeldt-Jakob Disease

Bovine spongiform encephalopathy (BSE) is the only known zoonotic prion that causes variant Creutzfeldt-Jakob disease (vCJD) in humans. The major risk determinant for this disease is the polymorphic codon 129 of the human prion protein (Hu-PrP), where either methionine (Met(129)) or valine (Val(129)...

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Detalhes bibliográficos
Publicado no:Emerg Infect Dis
Main Authors: Fernández-Borges, Natalia, Espinosa, Juan Carlos, Marín-Moreno, Alba, Aguilar-Calvo, Patricia, Asante, Emmanuel A., Kitamoto, Tetsuyuki, Mohri, Shirou, Andréoletti, Olivier, Torres, Juan María
Formato: Artigo
Idioma:Inglês
Publicado em: Centers for Disease Control and Prevention 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572891/
https://ncbi.nlm.nih.gov/pubmed/28820136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid2309.161948
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