Deciphering the pathogenesis of sporadic Creutzfeldt-Jakob disease with codon 129 M/V and type 2 abnormal prion protein

BACKGROUND: Sporadic Creutzfeldt-Jakob disease is classified according to the genotype at polymorphic codon 129 (M or V) of the prion protein (PrP) gene and the type (1 or 2) of abnormal isoform of PrP (PrP(Sc)) in the brain. The most complicated entity in the current classification system is MV2, s...

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Detalhes bibliográficos
Main Authors: Kobayashi, Atsushi, Iwasaki, Yasushi, Otsuka, Hiroyuki, Yamada, Masahito, Yoshida, Mari, Matsuura, Yuichi, Mohri, Shirou, Kitamoto, Tetsuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833290/
https://ncbi.nlm.nih.gov/pubmed/24252157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-1-74
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