Transmission Properties of Atypical Creutzfeldt-Jakob Disease: a Clue to Disease Etiology?

The genotype at polymorphic codon 129 of the PRNP gene has a profound influence on both phenotypic expression and prion strain susceptibility in humans. For example, while the most common sporadic Creutzfeldt-Jakob disease (CJD) subtype, sporadic CJD-MM1 (M1 strain), induces a single phenotype after...

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Bibliographic Details
Published in:J Virol
Main Authors: Kobayashi, Atsushi, Parchi, Piero, Yamada, Masahito, Brown, Paul, Saverioni, Daniela, Matsuura, Yuichi, Takeuchi, Atsuko, Mohri, Shirou, Kitamoto, Tetsuyuki
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Prions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403436/
https://ncbi.nlm.nih.gov/pubmed/25609817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03183-14
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