Two distinct conformers of PrP(D) type 1 of sporadic Creutzfeldt–Jakob disease with codon 129VV genotype faithfully propagate in vivo

Current classifications of sporadic Creutzfeldt–Jakob disease (sCJD) identify five subtypes associated with different disease phenotypes. Most of these histopathological phenotypes (histotypes) co-distribute with distinct pairings of methionine (M)/valine (V) genotypes at codon 129 of the prion prot...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Cali, Ignazio, Espinosa, Juan Carlos, Nemani, Satish K., Marin-Moreno, Alba, Camacho, Manuel V., Aslam, Rabail, Kitamoto, Tetsuyuki, Appleby, Brian S., Torres, Juan Maria, Gambetti, Pierluigi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7995586/
https://ncbi.nlm.nih.gov/pubmed/33766126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01132-7
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