Two distinct conformers of PrP(D) type 1 of sporadic Creutzfeldt–Jakob disease with codon 129VV genotype faithfully propagate in vivo

Current classifications of sporadic Creutzfeldt–Jakob disease (sCJD) identify five subtypes associated with different disease phenotypes. Most of these histopathological phenotypes (histotypes) co-distribute with distinct pairings of methionine (M)/valine (V) genotypes at codon 129 of the prion prot...

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Библиографические подробности
Опубликовано в: :Acta Neuropathol Commun
Главные авторы: Cali, Ignazio, Espinosa, Juan Carlos, Nemani, Satish K., Marin-Moreno, Alba, Camacho, Manuel V., Aslam, Rabail, Kitamoto, Tetsuyuki, Appleby, Brian S., Torres, Juan Maria, Gambetti, Pierluigi
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2021
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7995586/
https://ncbi.nlm.nih.gov/pubmed/33766126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01132-7
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