Sheep-Passaged Bovine Spongiform Encephalopathy Agent Exhibits Altered Pathobiological Properties in Bovine-PrP Transgenic Mice

Sheep can be experimentally infected with bovine spongiform encephalopathy (BSE), and the ensuing disease is similar to scrapie in terms of pathogenesis and clinical signs. BSE infection in sheep is an animal and human health concern. In this study, the transmission in BoPrP-Tg110 mice of prions fro...

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Autori principali: Espinosa, Juan Carlos, Andréoletti, Olivier, Castilla, Joaquín, Herva, María Eugenia, Morales, Mónica, Alamillo, Elia, San-Segundo, Fayna Díaz, Lacroux, Caroline, Lugan, Séverine, Salguero, Francisco Javier, Langeveld, Jan, Torres, Juan María
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797487/
https://ncbi.nlm.nih.gov/pubmed/17079295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01356-06
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