Detection of PrP(res) in peripheral tissue in pigs with clinical disease induced by intracerebral challenge with sheep-passaged bovine spongiform encephalopathy agent

Bovine spongiform encephalopathy (BSE) can be efficiently transmitted to pigs via intracerebral inoculation. A clear link has been established between the consumption of products of bovine origin contaminated with the BSE agent and the development of variant Creutzfeldt-Jakob disease in humans. Smal...

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Udgivet i:PLoS One
Main Authors: Hedman, Carlos, Otero, Alicia, Douet, Jean-Yves, Lacroux, Caroline, Lugan, Séverine, Filali, Hicham, Corbière, Fabien, Aron, Naima, Badiola, Juan José, Andréoletti, Olivier, Bolea, Rosa
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033439/
https://ncbi.nlm.nih.gov/pubmed/29975760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199914
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