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Detection of PrP(res) in peripheral tissue in pigs with clinical disease induced by intracerebral challenge with sheep-passaged bovine spongiform encephalopathy agent

Bovine spongiform encephalopathy (BSE) can be efficiently transmitted to pigs via intracerebral inoculation. A clear link has been established between the consumption of products of bovine origin contaminated with the BSE agent and the development of variant Creutzfeldt-Jakob disease in humans. Smal...

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發表在:PLoS One
Main Authors: Hedman, Carlos, Otero, Alicia, Douet, Jean-Yves, Lacroux, Caroline, Lugan, Séverine, Filali, Hicham, Corbière, Fabien, Aron, Naima, Badiola, Juan José, Andréoletti, Olivier, Bolea, Rosa
格式: Artigo
語言:Inglês
出版: Public Library of Science 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033439/
https://ncbi.nlm.nih.gov/pubmed/29975760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199914
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