Transgenic Mice Expressing Porcine Prion Protein Resistant to Classical Scrapie but Susceptible to Sheep Bovine Spongiform Encephalopathy and Atypical Scrapie

How susceptible pigs are to infection with sheep prions is unknown. We show, through transmission experiments in transgenic mice expressing porcine prion protein (PrP), that the susceptibility of this mouse model to bovine spongiform encephalopathy (BSE) can be enhanced after its passage in ARQ shee...

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Autori principali: Espinosa, Juan-Carlos, Herva, María-Eugenia, Andréoletti, Olivier, Padilla, Danielle, Lacroux, Caroline, Cassard, Hervé, Lantier, Isabelle, Castilla, Joaquin, Torres, Juan-María
Natura: Artigo
Lingua:Inglês
Pubblicazione: Centers for Disease Control and Prevention 2009
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815954/
https://ncbi.nlm.nih.gov/pubmed/19751582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid1508.081218
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