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Different Behavior toward Bovine Spongiform Encephalopathy Infection of Bovine Prion Protein Transgenic Mice with One Extra Repeat Octapeptide Insert Mutation

In humans, insert mutations within the repetitive octapeptide region of the prion protein gene (Prnp) are often associated with familial spongiform encephalopathies. In this study, transgenic mice expressing bovine PrP (boTg mice) bearing an additional octapeptide insertion to the wild type (seven o...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Castilla, J., Gutiérrez-Adán, A., Brun, A., Pintado, B., Parra, B., Ramírez, M. A., Salguero, F. J., Díaz San Segundo, F., Rábano, A., Cano, M. J., Torres, J. M.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730430/
https://ncbi.nlm.nih.gov/pubmed/14999066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3811-03.2004
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