Subclinical Bovine Spongiform Encephalopathy Infection in Transgenic Mice Expressing Porcine Prion Protein

The bovine-porcine species barrier to bovine spongiform encephalopathy (BSE) infection was explored by generating transgenic mouse lines expressing the porcine prion protein (PrP) gene. All of the porcine transgenic (poTg) mice showed clinical signs of BSE after intracerebral inoculation with a high...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Castilla, Joaquín, Gutiérrez-Adán, Alfonso, Brun, Alejandro, Doyle, Deirdre, Pintado, Belén, Ramírez, Miguel A., Salguero, Francisco J., Parra, Beatriz, Segundo, Fayna Díaz San, Sánchez-Vizcaíno, José M., Rogers, Mark, Torres, Juan M.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2004
Subjects:
Neurobiology of Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729370/
https://ncbi.nlm.nih.gov/pubmed/15163699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5400-03.2004
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