Twist1 in Infiltrating Macrophages Attenuates Kidney Fibrosis via Matrix Metallopeptidase 13–Mediated Matrix Degradation

BACKGROUND: Following an acute insult, macrophages regulate renal fibrogenesis through the release of various factors that either encourage the synthesis of extracellular matrix synthesis or the degradation of matrix via endocytosis, proteolysis, or both. However, the roles of infiltrating versus re...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Ren, Jiafa, Zhang, Jiandong, Rudemiller, Nathan P., Griffiths, Robert, Wen, Yi, Lu, Xiaohan, Privratsky, Jamie R., Gunn, Michael D., Crowley, Steven D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2019
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727252/
https://ncbi.nlm.nih.gov/pubmed/31315922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018121253
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