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Classical Dendritic Cells Mediate Hypertension by Promoting Renal Oxidative Stress and Fluid Retention

Fms-like tyrosine kinase 3 ligand (FLT3L) stimulates the development of classical dendritic cells (DCs). Here we tested the hypothesis that classical DCs drive blood pressure elevation by promoting renal fluid retention. FLT3L deficient (FLT3L(−/−)) mice that lack classical DCs in the kidney had mea...

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Bibliographische Detailangaben
Veröffentlicht in:Hypertension
Hauptverfasser: Lu, Xiaohan, Rudemiller, Nathan P., Privratsky, Jamie R., Ren, Jiafa, Wen, Yi, Griffiths, Robert, Crowley, Steven D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004279/
https://ncbi.nlm.nih.gov/pubmed/31786985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13667
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