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The transcription factor Twist1 in the distal nephron but not in macrophages propagates aristolochic acid nephropathy.
Tubulointerstitial disease in the kidney culminates in renal fibrosis that portents organ failure. Twist1, a basic helix-loop-helix protein 38 transcription factor, regulates several essential biological functions, but inappropriate Twist1 activity in the kidney epithelium can trigger kidney fibroge...
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| Pubblicato in: | Kidney Int |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6943184/ https://ncbi.nlm.nih.gov/pubmed/31685313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2019.07.016 |
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