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The transcription factor Twist1 in the distal nephron but not in macrophages propagates aristolochic acid nephropathy.

Tubulointerstitial disease in the kidney culminates in renal fibrosis that portents organ failure. Twist1, a basic helix-loop-helix protein 38 transcription factor, regulates several essential biological functions, but inappropriate Twist1 activity in the kidney epithelium can trigger kidney fibroge...

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Dades bibliogràfiques
Publicat a:Kidney Int
Autors principals: Ren, Jiafa, Rudemiller, Nathan P., Wen, Yi, Lu, Xiaohan, Privratsky, Jamie R., Crowley, Steven D.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943184/
https://ncbi.nlm.nih.gov/pubmed/31685313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2019.07.016
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