Stimulating Type 1 Angiotensin Receptors on T Lymphocytes Attenuates Renal Fibrosis

Most forms of chronic kidney disease culminate in renal fibrosis that heralds organ failure. In contrast to the protective effects of globally blocking type 1 angiotensin (AT(1)) receptors throughout the body, activating AT(1) receptors directly on immune cells may serve protective functions. Howeve...

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Udgivet i:Am J Pathol
Main Authors: Wen, Yi, Rudemiller, Nathan P., Zhang, Jiandong, Jeffs, Alexander D., Griffiths, Robert, Lu, Xiaohan, Ren, Jiafa, Privratsky, Jamie, Crowley, Steven D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521889/
https://ncbi.nlm.nih.gov/pubmed/31000207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.02.004
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