TNF-α in T lymphocytes attenuates renal injury and fibrosis during nephrotoxic nephritis

Nephrotoxic serum nephritis (NTN) models immune-mediated human glomerulonephritis and culminates in kidney inflammation and fibrosis, a process regulated by T lymphocytes. TNF-α is a key proinflammatory cytokine that contributes to diverse forms of renal injury. Therefore, we posited that TNF-α from...

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Gepubliceerd in:Am J Physiol Renal Physiol
Hoofdauteurs: Wen, Yi, Rudemiller, Nathan P., Zhang, Jiandong, Robinette, Taylor, Lu, Xiaohan, Ren, Jiafa, Privratsky, Jamie R., Nedospasov, Sergei A., Crowley, Steven D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985827/
https://ncbi.nlm.nih.gov/pubmed/31736350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00347.2019
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