Mechanism of Partial Agonism at NMDA Receptors for a Conformationally Restricted Glutamate Analog

The NMDA ionotropic glutamate receptor is ubiquitous in mammalian central neurons. Because partial agonists bind to the same site as glutamate but induce less channel activation, these compounds provide an opportunity to probe the mechanism of activation of NMDA-type glutamate receptors. Molecular d...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Erreger, Kevin, Geballe, Matthew T., Dravid, Shashank M., Snyder, James P., Wyllie, David J. A., Traynelis, Stephen F.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Cellular/Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725262/
https://ncbi.nlm.nih.gov/pubmed/16120788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1613-05.2005
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