Mechanism of Partial Agonism at NMDA Receptors for a Conformationally Restricted Glutamate Analog

The NMDA ionotropic glutamate receptor is ubiquitous in mammalian central neurons. Because partial agonists bind to the same site as glutamate but induce less channel activation, these compounds provide an opportunity to probe the mechanism of activation of NMDA-type glutamate receptors. Molecular d...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Erreger, Kevin, Geballe, Matthew T., Dravid, Shashank M., Snyder, James P., Wyllie, David J. A., Traynelis, Stephen F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2005
Pynciau:
Cellular/Molecular
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725262/
https://ncbi.nlm.nih.gov/pubmed/16120788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1613-05.2005
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