Mechanism of Partial Agonism at NMDA Receptors for a Conformationally Restricted Glutamate Analog

The NMDA ionotropic glutamate receptor is ubiquitous in mammalian central neurons. Because partial agonists bind to the same site as glutamate but induce less channel activation, these compounds provide an opportunity to probe the mechanism of activation of NMDA-type glutamate receptors. Molecular d...

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Foilsithe in:J Neurosci
Main Authors: Erreger, Kevin, Geballe, Matthew T., Dravid, Shashank M., Snyder, James P., Wyllie, David J. A., Traynelis, Stephen F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2005
Ábhair:
Cellular/Molecular
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725262/
https://ncbi.nlm.nih.gov/pubmed/16120788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1613-05.2005
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