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Mechanism of Partial Agonism at NMDA Receptors for a Conformationally Restricted Glutamate Analog
The NMDA ionotropic glutamate receptor is ubiquitous in mammalian central neurons. Because partial agonists bind to the same site as glutamate but induce less channel activation, these compounds provide an opportunity to probe the mechanism of activation of NMDA-type glutamate receptors. Molecular d...
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| 發表在: | J Neurosci |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Society for Neuroscience
2005
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6725262/ https://ncbi.nlm.nih.gov/pubmed/16120788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1613-05.2005 |
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