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Stabilization of μ-opioid receptor facilitates its cellular translocation and signaling
The G-protein-coupled μ-opioid receptor (μ-OR) mediates the majority of analgesia effects for morphine and other pain relievers. Despite extensive studies of its structure and activation mechanisms, the inherently low maturation efficiency of μ-OR represents a major hurdle to understanding its funct...
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| Publicado no: | Proteins |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6718349/ https://ncbi.nlm.nih.gov/pubmed/31141214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25751 |
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