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Differential Regulation of 6- and 7-Transmembrane Helix Variants of μ-Opioid Receptor in Response to Morphine Stimulation
The pharmacological effect of opioids originates, at the cellular level, by their interaction with the μ-opioid receptor (mOR) resulting in the regulation of voltage-gated Ca(2+) channels and inwardly rectifying K(+) channels that ultimately modulate the synaptic transmission. Recently, an alternati...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4640872/ https://ncbi.nlm.nih.gov/pubmed/26554831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142826 |
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