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μ-Opioid receptor 6-transmembrane isoform: a potential therapeutic target for new effective opioids
The μ-opioid receptor (MOR) is the primary target for opioid analgesics. MOR induces analgesia through the inhibition of second messenger pathways and the modulation of ion channels activity. Nevertheless, cellular excitation has also been demonstrated, and proposed to mediate reduction of therapeut...
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| Publicado no: | Prog Neuropsychopharmacol Biol Psychiatry |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4646084/ https://ncbi.nlm.nih.gov/pubmed/25485963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pnpbp.2014.11.009 |
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