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Structural Mechanism of S-Adenosyl Methionine Binding to Catechol O-Methyltransferase

Methyltransferases possess a homologous domain that requires both a divalent metal cation and S-adenosyl-L-methionine (SAM) to catalyze its reactions. The kinetics of several methyltransferases has been well characterized; however, the details regarding their structural mechanisms have remained uncl...

詳細記述

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書誌詳細
主要な著者: Tsao, Douglas, Diatchenko, Luda, Dokholyan, Nikolay V.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164188/
https://ncbi.nlm.nih.gov/pubmed/21904625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024287
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