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3D chromosomal landscapes in hematopoiesis and immunity

Epigenetic dysregulation plays a profound role in the pathogenesis of hematological malignancies, which is often the result of somatic mutations of chromatin regulators. Previously, these mutations were largely considered to alter gene expression in two dimensions, by activating or repressing chroma...

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Detalhes bibliográficos
Publicado no:Trends Immunol
Main Authors: Kloetgen, Andreas, Thandapani, Palaniraja, Tsirigos, Aristotelis, Aifantis, lannis
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718347/
https://ncbi.nlm.nih.gov/pubmed/31422902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2019.07.003
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