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3D chromosomal landscapes in hematopoiesis and immunity

Epigenetic dysregulation plays a profound role in the pathogenesis of hematological malignancies, which is often the result of somatic mutations of chromatin regulators. Previously, these mutations were largely considered to alter gene expression in two dimensions, by activating or repressing chroma...

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Detalles Bibliográficos
Publicado en:Trends Immunol
Main Authors: Kloetgen, Andreas, Thandapani, Palaniraja, Tsirigos, Aristotelis, Aifantis, lannis
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718347/
https://ncbi.nlm.nih.gov/pubmed/31422902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2019.07.003
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