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3D chromosomal landscapes in hematopoiesis and immunity
Epigenetic dysregulation plays a profound role in the pathogenesis of hematological malignancies, which is often the result of somatic mutations of chromatin regulators. Previously, these mutations were largely considered to alter gene expression in two dimensions, by activating or repressing chroma...
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| Publicat a: | Trends Immunol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6718347/ https://ncbi.nlm.nih.gov/pubmed/31422902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2019.07.003 |
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