Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia

Three-dimensional (3D) chromatin architectural differences can influence the integrity of topologically associating domains (TADs) and rewire specific enhancer-promoter interactions, impacting gene expression and leading to human disease. Here, we investigate the 3D chromatin architecture in T cell...

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Vydáno v:Nat Genet
Hlavní autoři: Kloetgen, Andreas, Thandapani, Palaniraja, Ntziachristos, Panagiotis, Ghebrechristos, Yohana, Nomikou, Sofia, Lazaris, Charalampos, Chen, Xufeng, Hu, Hai, Bakogianni, Sofia, Wang, Jingjing, Fu, Yi, Boccalatte, Francesco, Zhong, Hua, Paietta, Elisabeth, Trimarchi, Thomas, Zhu, Yixing, Van Vlierberghe, Pieter, Inghirami, Giorgio G, Lionnet, Timothee, Aifantis, Iannis, Tsirigos, Aristotelis
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138649/
https://ncbi.nlm.nih.gov/pubmed/32203470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-020-0602-9
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