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Lack of multidrug resistance-associated protein 4 (Mrp4) alters the kinetics of acetaminophen toxicity
Acetaminophen (APAP) overdose is the most frequent cause of drug-induced liver injury in humans and a common chemical model to investigate genetic determinants of susceptibility to drug-induced liver injury (DILI). Previous studies performed in our laboratory identified the efflux transporter multid...
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| 發表在: | Toxicol Rep |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6717103/ https://ncbi.nlm.nih.gov/pubmed/31485416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2019.08.005 |
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