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The modulation of transcriptional expression and inhibition of multidrug resistance associated protein 4 (MRP4) by analgesics and their primary metabolites

During the course of a toxic challenge, changes in gene expression can manifest such as induction of metabolizing enzymes as a compensatory detoxification response. We currently report that a single 400 mg/kg acetaminophen (APAP) dose to C57BL/6J mice led to an increase in multidrug resistance-assoc...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Curr Res Toxicol
मुख्य लेखकों: Scialis, Renato J., Ghanem, Carolina I., Manautou, José E.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320619/
https://ncbi.nlm.nih.gov/pubmed/34345835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.crtox.2020.04.002
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